As a separation business, I don't just separate how it should look, I separate for what you need it to be.
Many ways to do this. The question I always ask is, Does your customer want to spend the money on getting it to look exactly like this? If not, what is the budget for pint cost? How many colors can I use.
I can do it in 1 color, 2 colors on up to max out your press. FOr this job to be done (as you see it),
1 Base white (at a minimum). Two whites are best (for the outline on type. I prefer not to make it too heavy on that first white. Some printers use only thin inks (even for the whites) so that often demands a 2nd white for this.
2 Bright Green
3 Medium Blue - referencing type
4 Medium brown
5 Process Black
A top white if necessary would be the 6th.