smaller volume of air is easier to AC, but also easier to fill with fumes/smoke. we often have to open all the doors and blow everything out. for a long time we could not keep the doors closed.
ceiling tiles gather the dust bunnies. you'll have to clean it somewhat regularly to avoid the fire hazard.
our electric bill is more than $1k higher in the summer, well worth it though.
the ceiling might be too low for some of the presses with tall light tree. make sure you measure.
all your the drop tiles will yellow from the fumes. it is more prominent by the dryer. your hoods will not catch all. You can repaint them though.
if you have sprinklers, they have to come through the tiles. the sprinkler heads will get covered in lint, be careful with those.
pierre