"He who marches out of step hears another drum." ~ Ken Kesey
I lift the lid, put my screen down, put a black piece of foam board in the back and a large heavy platen inside of the screen on top of the foam board which is sitting against the screen. I can't imagine the screen isn't getting bad contact on the glass.
Ideally, when held up to a light source, films won't seem as you're looking through dark sunglasses. You should be able to discern anything through the dark areas (like moving fingers) It's also not impossible that your films are patchy, more likely than uneven light with all of your new tubes.How are you making your films? Printer, ink, specific media?Exposure times go up exponentially with coarser meshes. Assuming both are white, a 110 may easily take half again as long as a 180.With a starting time of 45 seconds, I'd do a half dozen steps ranging from 25 to 90 seconds. When you find a potential sweet spot, you can narrow it down.Remember, a test should be done for each emulsion, each different mesh count, mesh color, and coating technique.