Opportunity is missed by most people because it is dressed in overalls and looks like work. - Thomas Edison
There was a sep program years ago I think from Squaredot.com that did this, for some reason it didn't catch fire and back then I knew about what I know now nothing, but saw a lot of very nice prints side by side to using round dots and the square's used less color and got the same result's. Had to do a little digging but found it Screenprint Separator I guess it's still on the market use to be market with Posjet film which I used back in the day, I want to say David Crain created the program.
they are really just more tools for the tool box Darryl. We almost never index anything here anymore, years between them actually. If you learn the process manually, then it can tweak your creative juices. The thing I generally find is that they look fabulous from a few feet away, a little less so up close, so it can be a hard sell. I had a Disney shirt years ago done this way, I think it had about 14 colors I counted, and very fine "squares"...Steve