Opportunity is missed by most people because it is dressed in overalls and looks like work. - Thomas Edison
The last time I sent a multi color design to Ace for transfers, I was surprised that they told me to not worry about reg marks fitting because they don't need them with their DTS system.
Imagine a CTS with integrated registration system. I'm telling ya.
Hope this makes sense. I know I tend to wander, but I'm trying to help you understand the benefits.